It follows their narrow 20 -24 defeat by the Leicester Tigers last Saturday.
Phil Dollman and Jack Nowell both return for the first time this season, taking over from Ceri Sweeney and Jack Arnott.
Two changes have been made to the starting line-up with Ben Moon coming in for Carl Rimmer, while Damian Welch comes in instead of Ryan Caldwell.
Tens of millions to be invested in Devon's buses
Local leaders will decided how money is spent
Fawlty Towers: The Play - REVIEW
Chaotic tribute act to renowned series
Lib Dems hold Exmouth seat in by-election
Fran McElhone wins the Halsdon seat
Paignton YMCA moves into former Mormon chapel
Our new home is absolutely ideal'
Homes to be built on former Exeter driving range
More than 50 houses planned
Extra staff to improve adult response times
Two-day target only hit in one in every 10
