They're among 53 immediately making the change
Three Boots stores in Devon have scrapped plastic bags from today.
The shops in Exeter High Street, Salcombe and Plymouth will offer paper bags instead - with all profits donated to BBC Children in Need.
They're part of 53 stores adopting the change today, whilst all 2,485 sites will follow suit by early next year.
Seb James, managing director said: “Plastic waste is undoubtedly one of the most important issues around the world today with TV shows like Blue Planet highlighting the effects of plastic pollution.
"This year, we are transforming Boots as we celebrate 170 years, and the move to unbleached paper bags is another pivotal moment in that journey.
"There is no doubt that our customers expect us to act and this change signifies a huge step away from our reliance on plastic.”