Junction 29 of the M5 and the westbound carriageway of the A30 will be closed for five nights from tonight.
The restrictions will apply from 8 pm until 6 am while resurfacing and other work is carried out.
Further overnight closures are planned for later this month and during September.
Hospitals brace for Junior Doctor strikes
From frontline to picket lines
£40k of sports club machinery stolen
Thieves target lockups
Devon duo set for Sheep Shearing "Olympics"
International champions aim for world title
14-year-old girl missing from Exeter
Lola Tinkler was last seen on Saturday
Man reattaches flags moments after removal
He scaled his ladder as council contractors used a cherry picker
