It follows their narrow 20 -24 defeat by the Leicester Tigers last Saturday.
Phil Dollman and Jack Nowell both return for the first time this season, taking over from Ceri Sweeney and Jack Arnott.
Two changes have been made to the starting line-up with Ben Moon coming in for Carl Rimmer, while Damian Welch comes in instead of Ryan Caldwell.
Devon rapist jailed for 10 years
Philip Street told victim it 'was our secret'
75 homes pledged near Buckfastleigh
45 percent to be affordable
Residents return home after WW2 bomb detonated
Emergency services thank Plymouth residents
WW2 bomb found in Plymouth to be detonated today
Thousands evacuated from Southway
Man jailed for hiding knife in sock in Barnstaple
Callum Booth sentenced to 40 weeks
Brixham campsite row ahead of busy weekend
MP steps in as council 'considers enforcement'
